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                    產品名稱 : YM155
                    型號 : CR1009
                    CAS : 781661-94-7
                    備注:所有產品僅用作科學研究,我們不為任何個人用途提供產品和服務 : 
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                    Description of:YM155
                    YM155, a novel small molecule survivin inhibitor, suppressed expression of survivin and induced apoptosis in PC-3 and PPC-1 human HRPC cell lines at 10 nmol/L. In a s.c.xenogr afted PC-3 tumor model in mice, 3-day continuous infusions of YM155 at 3 to 10 mg/kg induced massive tumor regression accompanied by suppression of intratumoral survivin.Pharmacokinetic analyses indicated that YM155 is highly distributed to tumors and at concentrations f20-fold higher than those in plasma.

                    Theoretical analysis:YM155
                    M.Wt: 443.29
                    Formula: C20H19BrN4O3
                    Solubility: DMSO
                    Purity: >99%
                    CAS No: 781661-94-7
                    Storage: at -20C 2 years

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                    Quality control data:
                    Quality Control by H-NMR,C-NMR,LC-MS,HPLC.
                    Product will be shipped with supporting analytical data.
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